Chemotherapy of Theileria parva lawrencei infections in cattle with halofuginone.
نویسندگان
چکیده
Halofuginone lactate, given once orally at a dosage rate of 1,2 mg/kg body mass on the 1st, 3rd or 5th days of fever, resulted in the recovery of only 1 out of 5 splenectomized cattle. Three splenectomized animals, treated on the 1st as well as the 4th day of fever, recovered and were then carriers. Six untreated controls all died. The potential value of a chemotherapeutic agent for Theileria parva lawrencei infections in South Africa is discussed.
منابع مشابه
Chemotherapy of East Coast fever. Treatment of infections induced by isolates of Theileria parva with halofuginone.
Cattle were infected with three isolates of Theileria parva and treated with halofuginone lactate during acute clinical disease. The health, weight gain and carrier state of the cattle were monitored for 15 months. Limited treatment rapidly reduced fever and parasitosis but parasite recrudescences occurred and 12 out of 21 treated cattle died. Persistent carrier states were identified with two ...
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Three cattle, which had been experimentally infected with Theileria parva lawrencei and maintained as carriers of the infection, were each infested simultaneously with clean nymphal Rhipicephalus appendiculatus and Rhipicephalus zambeziensis in ear bags on separate ears. After moulting, the ensuing adult ticks were fed on rabbits for 4 days and their salivary glands were examined for infective ...
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ورودعنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 50 1 شماره
صفحات -
تاریخ انتشار 1983